The Nemechek Protocol seeks to decrease brain inflammation by addressing small intestinal bacterial overgrowth (often called SIBO). There is an important connection between the brain and the gut, so treating SIBO is a sensible way to address brain inflammation–which itself is a common problem for our kids with autism.
What Does the Nemechek Protocol Involve?
The Nemechek Protocol addresses SIBO by supplementing with:
- Omega 3 fatty acids (aka fish oils)
- Inulin (a prebiotic fiber given in gummy or powder form)
The protocol has helped many people, but some patients have an adverse reaction to the prebiotic fiber.
Does the Nemechek Protocol Work for Everyone?
While the Nemechek Protocol works very well for some, it does not work for everyone. A major reason for this is that the protocol does not necessarily identify and address the root cause of SIBO.
Treating SIBO is challenging, and the condition often recurs if the root cause is not resolved. Potential root causes include:
- Lack of stomach acid, potentially caused by H. Pylori infection
- Backup of fecal matter from the large intestine to the small intestine
Treating these root causes in the digestive system is a more reliable way to help your child resolve SIBO for good, which in turn will improve their brain function by reducing inflammation.

Be gentle with yourself. You’re doing a great job.
I hope this information has been helpful to you as part of creating Your Autism Game Plan.
Do you have a topic you’d like to learn more about? Email me at joya@yourautismgameplan.com
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You might also like: Identifying and Treating SIBO and SIFO in Autistic Children